6 years plan
for
Ancient DNA
(Paleogenomics)
Lab @QU
Precision Medicine
QU-Health Precision Medicine RNG
Drug Development
Disease Diagnosis
Immunology
Objectives
Track presence/absence of pathogenic and deleterious mutations in ancient and modern human
Look at the distribution, variation, and effects of viruses
becoming non-infectious after some time
e.g. HERVs
becoming infectious after time
e.g. HTLV-1 & Lymphoma
trigger for other diseases
e.g. HHV-6 & multiple sclerosis
Ancient migratory patterns contributing to increased predisposition or resistance to diseases
To establish an ancient DNA lab @ QU with guidance from HMS
Grant
PPM
ARG

Disease/Conditions
Artherosclerosis
Obesity and dyslipidemia
Diabetes and insulin resistance

Team

Dr Mashael (CHS)
(Geneticist)

Dr Rozaimi (CHS)
(Computational Biologist)
Dr Houssein (CHS)
(Population geneticist)

Dr Sherine (CAS)
(Archaeologist)

Dr Hanaa Mousa (CMED)
(Immunologist)
Dr David Reich
(Paleogeneticist)
Dr Suad Al Fadhli
Dr Maryam Daneshpour

Partner
To provide ancient bone samples

To provide ancient samples

To provide sequencing service
To provide sequencing saervice
To provide ancient DNA analysis and training
To provide modern DNA
Cancer
Grant
ARG
PPM
Case study
Team
Dr Hamda Al Thawadi (CMED)
Dr Semir (CMED)
Forensic

Ethics
CILE (HBKU)
Dr Mohammed Ghaly

Conservation
Dugong
QU BRC
Turtle
Shark
Camel

History
Subtopic